dementia with Lewy bodies(English)

• age-associated synucleinopathy producing progressive cognitive decline (in which extrapyramidal motor features are often mild or absent, at least until the late stages) that interferes with normal life and daily activities. The two distinct clinical syndromes of DLB and PD/PDD share underlying pathomechanisms, while the reasons for the clinical heterogeneity may be due to different propagation patterns of α-syn pathology across different neuronal pathways. DLB is the preferred term for a variety of previously used clinical diagnoses including diffuse LB disease, LB dementia, dementia associated with cortical Lewy bodies, the LB variant of Alzheimer’s disease, and senile dementia of LB type; aka LBD
• AD, DCLB, DLBD, DSM, LB, LBVAD, PD, PDD, SDLT
• Dementia
• https://doi.org…3024-019-0306-8