HAVCR2

hepatitis A virus cellular receptor 2(English)

  • HCCs with a discrete population of PD1-high CD8+ T cells express TIM3 and/or LAG3 and produce low levels of IFNG and TNF in response to anti-CD3. Incubation of these cells with antibodies against PD1 and TIM3 or LAG3 further restore proliferation and production of cytokines
  • IFNG, HCC, TNF
  • Hepatology, Virology
  • https://doi.org…tro.2018.08.030