HODE

13-S-hydroxyoctadecadienoic acid(English)

  • a 12/15-lipoxygenase metabolite that induces mitochondrial dysfunction, with severe airway obstruction and neutrophilic airway inflammation. It modifies typical AAI to recapitulate many of the phenotypic features seen in severe steroid unresponsive asthma
  • AAI
  • Mitochondrion, Asthma
  • https://doi.org…598-017-09869-9