HSV-1

herpes simplex virus type 1(English)

  • a neurotropic human pathogen capable of causing a variety of clinical diseases although the majority of infected immunocompetent patients are asymptomatic. The specific clinical illness will be determined by the portal of virus entry, the competence of the host immune system, and whether the infection is primary or recurrent. Following a primary infection, HSV-1 establishes a latent state in sensory or autonomic ganglia that is maintained for the life of the host. Periodically, the latent virus can be reactivated by a variety of endogenous and exogenous stimuli to cause asymptomatic viral shedding or symptomatic recurrent infections within the distribution of the affected nerve
  • B-VEC, HSV, HSV-2
  • Infection, Virology
  • https://doi.org…9440(10)63595-X