nAChR

nicotinic acetylcholine receptor(English)

  • a transmembrane allosteric protein that mediates transduction of chemoelectric signals throughout the nervous system by opening an intrinsic ionic channel. This rapid pore opening enables flow of Na+, K+, and, in several instances, Ca2+ ions across the cell membrane. As a consequence, these receptors elicit fast changes in the membrane electric potential, but they also regulate transmission of electric signals by closing the pore through slower desensitization transitions. They play crucial physiological roles and, when altered, they cause pathologies in humans
  • α7nAChR, SIDS
  • Membranes, Signal transduction, Calcium, Physiology, Potassium, Sodium
  • https://doi.org…45046-9.01127-X