uridine phosphorylase 1(English)

• plays a vital role in uridine metabolism, maintaining homeostasis and aiding pyrimidine salvage. It cleaves uridine to uracil and ribose-1-phosphate (R1P), supporting glycolysis, especially when nutrients are limited. In tumors with low glucose, UPP1 utilizes ribose from uridine to sustain tumor cell metabolism, enhancing their growth and survival
• AKT, CyTOF, LUAD, mTOR, PDO, PI3K, TME
• Oncology, Metabolism, Pulmonology
• https://doi.org…467-024-45340-w