adenosine deaminase acting on RNA 1(English)

• catalyzes the conversion of adenosine to inosine in double-stranded RNAs, which is critical to prevent autoinflammatory responses mediated by activation of the type I IFN (interferon) signaling. A critical regulator of PASMC homeostasis
• AT2, A-to-I, dsRNA, eIF2α, I:C, IFN, IFN-β, IFNAR1, IPAH, ISG, JACUSA, MAVS, MDA5, PAH, PASMC, Pdpn, PH, PKR, RNA-seq, RVH, RVSP, siADAR, siCtrl, SMA, Sp-c, TBK1, ADAR, AT1
• Cardiology, Myocyte / muscle, Regulation / control, Immunology, Pulmonology
• https://doi.org…SAHA.125.326235