aPDT

antimicrobial photodynamic therapy(English)

  • employs a photoreactive dye photosensitizer in combination with visible light and molecular oxygen. Following light absorption, the photochemical reactions lead to the generation of reactive oxygen species. ROS-mediated damage to proteins and lipids impairs function of the bacterial cellular structures and subsequently causes the eradication of microorganisms. This method is gaining increasing attention because of the multitargeted nature of the photosensitization process and resulting nonspecific mechanism of action. Some nanocarriers improve photosensitizers’ ROS yield or act as photosensitizers themselves
  • ROS
  • Microbiology, Therapeutic approaches, Bacteriology
  • https://doi.org…46152-8.00021-4