amyloid precursor protein-like(English)

• a single APP homologue which is implied in neuronal wiring and axonal growth through the Wnt signaling pathway during development. Loss of function results in the dysregulation of endolysosomal function in neurons, with a notable enlargement of early endosomal compartments followed by neuronal cell death and the accumulation of dead neurons in the brain during a critical period at a young age
• APP, LOF
• Neurons, Brain (dys)function, Regulation / control
• https://doi.org…al.pbio.3000703