C-C motif chemokine ligand 5(English)

• proinflammatory cytokine acting through PI3K-Akt signaling; it is also a negative regulator of GPR75, the receptor for the vasoconstrictor, 20-hydroxyeicosatetraecnoic acid. Upregulation increases infarct size and promotes heart failure following myocardial infarction. CCL5-mediated negative regulation of GPR75 function acts to ameliorate obesity and hypertension. Also denoted as RANTES
• CDHR2, CELSR2, CgA, CST1, DNAJB1, DNAJC9, eGFR, EpCAM, EPO, ERMAP, ESCRT-III, FABP5, FABP6, FDRq, GRP75, HSPA8, H-FABP, IGBP1, IGF1, IGFBP1, IST1, KYAT1, L-FABP, MMRM, MYDGF, NHE3, OTUB1, Pp2a, RANTES, RBP2, SGLT2i, SNCA, TBCA, TFF1, TfR1, UMOD, UMtCK, UROD, ACYP1, ATPIFI, CA2, CCL28
• Cardiology, Molecular biology
• https://doi.org…acc.2024.07.013