CLP

There are multiple definitions:

  1. common lymphoid progenitor(English)

  2. cecal ligation and puncture / perforation(English)

    • the most widely used animal model (consisting of the perforation of the cecum allowing the release of fecal material into the peritoneal cavity to generate an exacerbated immune response induced by polymicrobial infection) to study the etiology of sepsis, which is characterized by a set of systemic reactions in response to intensive and massive infection. During sepsis there are two established hemodynamic phases that may overlap. The initial phase (hyperdynamic) is defined as a massive production of proinflammatory cytokines and reactive oxygen species by macrophages and neutrophils that affects vascular permeability (leading to hypotension), cardiac function and induces metabolic changes culminating in tissue necrosis and organ failure. Consequently, the most common cause of mortality is acute kidney injury. The second phase (hypodynamic) is an anti-inflammatory process involving altered monocyte antigen presentation, decreased lymphocyte proliferation and function and increased apoptosis. This state known as immunosuppression or immune depression sharply increases the risk of nocosomial infections and ultimately, death. Because both phases of sepsis may cause irreversible and irreparable damage, it is essential to determine the immunological and physiological status of the patient. The same drug given at different stages of sepsis may be therapeutic or otherwise harmful or have no effect
    • fEPSP, HIP, LTP, BDNF, CAT, MD, MPO
    • Hemodynamics, Experimental animal, Brain (dys)function, Sepsis
    • https://doi.org/10.3791/2860
    • https://doi.org…54.2022.2154076

  3. consultation-liaison psychiatry(English)

    • young and upcoming subspecialty of psychiatry. The term is often used interchangeably with “psychosomatic medicine” which is understood as a discipline which deals with the understanding of “the interplay of biological and psychosocial factors in the development, course, and outcome of all disease
    • GHPU
    • Psychiatry
    • https://doi.org…ychiatry_255_17

  4. cleft lip and/or palate(English)