endosomal sorting complex required for transport(English)

• highly conserved set of protein complexes recognizes membrane proteins that are modified with ubiquitin molecules and thus marked for sorting to lysosomes (either as functional components of lysosomes or as substrates for lysosomal proteolysis). ESCRT complexes sort these cargoes to specific domains of endosomes and regulate both the inward invagination of these membrane regions and the scission of invaginated membrane buds to form intraluminal vesicles
• AIP1, MVB, STAM, EGF, HIV
• Membranes, Cell biology
• https://doi.org…science.1155750