3-hydroxy-3-methyl-glutaryl coenzyme A reductase(English)

• rate-limiting enzyme in the mevalonate pathway, catalyzing the conversion of HMG-CoA to mevalonic acid for cholesterol and isoprenoid biosynthesis. As a critical regulator of cellular cholesterol homeostasis, it is the primary target of statin drugs
• Pi/PPi, ABCC6, ALP, AS, ATP, AVC, AVCS, BMI, CCTA, DM, ENPP1, eGFR, GACI, HTN, LDL-C, Pi, PPi, PXE, TNAP
• Enzymes, Cardiology, Calcium, Pathology, Regulation / control
• https://doi.org…3/ehjci/jeaf247