LCA

There are multiple definitions:

  1. least costly alternative(English)

  2. last common ancesters(English)

  3. latent class analysis(English)

  4. lithocholic acid(English)

  5. Leber congenital amaurosis(English)

    • part of the spectrum of early-onset retinal dystrophy. It usually presents in the first few years of life, most often before the age of 1 year. The prevalence is about 1:80,000. Patients have wandering nystagmus, with reduced vision from birth. The fundus is almost normal to start with. Later, pigmentary disturbances develop. The best corrected visual acuity ranges from no light perception (in nearly one third of cases) to no better than 20/400, often with a hyperopic refraction (≥5.0 D). Patients have absent pupillary reflex and some of them have keratoconus (CRB1 and AIPL1). Oculodigital reflex (eye rubbing or poking) is a common association. Electroretinography responses are almost undetectable. Patients may have normal intelligence, but some studies suggest that as many as 20% of children with LCA without associated anomalies develop intellectual disability; aka congenital retinitis pigmentosa
    • BCVA, EORD, ERG, RP
    • Congenital disorders, Ophthalmology
    • https://doi.org…-319-95046-4_26
  6. left coronary artery(English)

  7. life cycle assessment(English)

  8. local Cobb angle(English)