NPM1

nucleophosmin 1(English)

  • protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia.
  • ARF, AML
  • Genetics, Proteins / proteomics
  • https://www.ncb…h.gov/gene/4869