RYGB

Roux-en-Y gastric bypass(English)

  • a popular weight loss surgery for adults with morbid obesity, with potential renal complications caused by abnormalities in oxalate handling after RYGB—i.e., enteric hyperoxaluria, calcium oxalate (CaOx) nephrolithiasis, and oxalate nephropathy. Hyperoxaluria is an adverse effect that occurs due to fat malabsorption and contributes to CaOx nephrolithiasis and oxalate nephropathy. Postoperative risk factors for CaOx kidney stones include low urine volume, high urine oxalate, and low urine citrate. Oxalate nephropathy is diagnosed by the characteristic kidney biopsy finding of acute tubular injury with oxalate crystals in renal tubules. Therapies to lower urine oxalate include lowering fat and oxalate intake, using calcium supplements to bind oxalate, bile acid sequestrants, or probiotics that degrade intraluminal oxalate; aka gastric bypass
  • CaOx
  • Adiposity, Surgery, Kidney and adrenals
  • https://doi.org…04011-9.00044-3