pregnane X receptor(English)
- nuclear receptor recognized as important to toxicology and involved in detoxification and drug interactions. PXR agonists can alleviate myocardial injury by regulating the p53-Bax/Bcl2 apoptosis pathway, providing a new basis for the mechanism and targeted therapy of HFsnEF
- AAA, ADR, AhR, AHR, APO, BA, CAR, CDCA, ED, FXR, GPR41, HFsnEF, LXR, MAPK, NTCP, OLFR78, PAG, PERK, Phe, PPAR, RXR, SCFA, TCA, TGR5, TMA, TMAO, TR, Trp, Tyr, 4βHC
- Receptors, Toxicology, Cardiology, Biomarker, Microbiome, Metabolism, Apoptosis
- https://doi.org…5931(03)00080-2
- https://doi.org…5085(03)00896-5
- https://doi.org…JAHA.123.031824
- https://doi.org…NAHA.123.067547
- https://doi.org…/fj.202503912rr