soluble fms-Like tyrosine kinase-1(English)
- an antiangiogenic factor expressed as an alternatively spliced variant of VEGFR-1 that lacks both the transmembrane and cytoplasmic domains. sFlt-1 binds VEGF and PlGF and blocks their angiogenic effects on VEGFR. sFlt-1 may also form a heterodimer with the surface membrane VEGFR-1 and inhibit its postreceptor signaling actions
- VEGRF-1, fms, PlGF, RUPP, VEGF, VEGFR
- Pregnancy
- https://doi.org…bts.2017.04.001