signal-regulatory protein alpha(English)

• gene associated with the recruitment of immune cells and immune inhibitory pathway. Upregulated in aging. A transmembrane glycoprotein and key receptor on macrophages that binds CD47 to inhibit phagocytosis. Also known as SHP substrate 1 (SHPS-1), and denoted as SIRPA
• CapEC, CD68, CGRP, CHAT, CNS, DAPI, EC, EGFR, LV, Lyve1, PDGFRA, p53, PNS, RV, SASP, SMC, snRNA-seq, TNF-α, TGF-ß, TUJ1, VSMC, WNT
• Genetics, Immunology, Aging, Cardiology, Regulation / control, Signal transduction
• https://doi.org…SAHA.125.327060
• https://doi.org…569-026-01260-4