systemic sclerosis(English)
- a chronic autoimmune disease with fibrosis, vascular wall damage, and disturbances of innate and acquired immune responses with autoantibody production as prominent features. Has specific subsets with different autoantibodies, and differences in the affected skin areas. Affects skin and internal organs, such as lungs, heart, kidneys, musculoskeletal system and the gastrointestinal tract. Skin sclerosis is a main symptom of SSc, evaluated using the modified Rodnan skin score (mRss) and an easily detectable marker of disease activity. The treatment of this autoimmune disease remains a challenge for clinicians. The occurrence of various symptoms and the involvement of many organs and systems make systemic sclerosis a multidisciplinary disease and require a holistic approach
- ssSSc, SWAP, TßRI-CA, CAR, PSS, GAG, MNC-SN, dcSSc, MRSS, SScCmp, CMP, ECG, PIP, mRss
- Autoimmunity, Dermatology, Vascular disease, Pulmonology
- https://dx.doi.…reum.2019.87619
- https://doi.org…46.2021.1970160
- https://doi.org…95.2021.1918864